Portobello, cremini, button, and shiitake mushrooms all have anti-cancer properties. “Mushrooms actually contain more antioxidants than pumpkins, carrots and tomatoes,” says Karen Graham, R.D., an Arizona-based integrative nutritionist. That’s because they’re loaded with ergothioneine and selenium, two immune-boosting antioxidants that cut your risk of cancer and cardiovascular disease. Also in their corner are beta-glucans, plant chemicals found especially in shiitake and maitake mushrooms, which supercharge the immune system and may prevent cancer. In fact, a study published in the International Journal of Cancer found that women who ate 10 grams of mushrooms per day were 64 percent less likely to develop breast cancer than those who didn’t.